Ibogaine is metabolized in the liver into noribogaine. This active metabolite remains in the body for at least four to six weeks after ingestion. Noribogaine decreases post-withdrawal drug cravings, and may have anti-depressive properties.
"Noribogaine will help to prevent post-treatment withdrawal symptoms..."
Mechanisms of Action
The anti-addictive properties of ibogaine, and its active metabolite noribogaine, result from a complex interaction between multiple neurotransmitter systems in the brain. The multiple mechanisms of action and its psychedelic properties contribute to ibogaine's ability to significantly reduce the symptoms of drug withdrawal and drug craving.